Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3808433 | 1.00 | CTSL (0.55) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3806619 | 0.93 | CTSL (0.57) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811496 | 0.92 | CTSL (0.54) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810290 | 0.92 | CTSL (0.54) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811083 | 0.92 | CTSL (0.56) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810701 | 0.91 | CTSL (0.53) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3810713 | 0.90 | CTSL (0.52) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3815645 | 0.90 | TSHR (0.44) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3815030 | 0.90 | TSHR (0.44) | CTSLCTSSCTSKCTSCCTSB | |
| SCHEMBL3811475 | 0.89 | CTSL (0.55) | CTSLCTSSCTSKCTSCCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129365-A1 | CATHEPSIN C INHIBITORS | GLAXO GROUP LIMITED (GB) | 2009-10-22 | — | — | WO | claimed |