Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 20/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 8/20 | 0.65 |
| ▸ | DRD2 | P14416 | 7/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834543 | 0.82 | ADRB2 (0.69) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801042 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801962 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1798743 | 0.79 | ADRB2 (0.92) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1798742 | 0.79 | ADRB2 (0.92) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801045 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1801961 | 0.79 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1798562 | 0.78 | ADRB2 (0.91) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1798564 | 0.78 | ADRB2 (0.91) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL1800695 | 0.78 | ADRB2 (1.00) | ADRB2ADRB1ADRA1DDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529038-B1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2009-10-07 | — | — | EP | claimed |