SCHEMBL3838546

SCHEMBL3838546

FC(F)(F)CC(F)(F)n1cccn1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.32
KCNN4 O15554 1/20 0.32
KCNA3 P22001 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28206207 0.78 KCNN4 (0.32) ADORA2AKCNN4KCNA3
SCHEMBL154791 0.74
SCHEMBL8639745 0.70
SCHEMBL27936120 0.70
SCHEMBL3843381 0.70 KCNN4 (0.38) KCNN4KCNA3
SCHEMBL7694127 0.69 KCNN4 (0.36) KCNN4KCNA3
SCHEMBL1304909 0.68 FDPS (0.38) ADORA2A
Formaldehyde SCHEMBL28535625 0.68 KCNN4 (0.33) KCNN4KCNA3
SCHEMBL3838541 0.68 KCNN4 (0.31) KCNN4KCNA3
SCHEMBL25340675 0.67 KCNN4 (0.33) KCNN4KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1727804-B1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2009-11-04 EP disclosed
EP-1727804-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2006-12-06 EP disclosed
WO-2005095351-A1 N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES BAYER CROPSCIENCE AG (DE) 2005-10-13 WO disclosed