Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838842 | 0.88 | PTGDR2 (0.46) | ABCB11PTGDR2DDR1 | |
| SCHEMBL2099776 | 0.83 | PTGDR2 (0.69) | ABCB11PTGDR2 | |
| SCHEMBL2101327 | 0.81 | ABCB11 (0.55) | ABCB11PTGDR2 | |
| SCHEMBL2101477 | 0.81 | ABCB11 (0.81) | ABCB11PTGDR2 | |
| SCHEMBL2102331 | 0.81 | ABCB11 (0.81) | ABCB11PTGDR2 | |
| SCHEMBL2101324 | 0.79 | ABCB11 (0.65) | ABCB11PTGDR2 | |
| SCHEMBL5174343 | 0.78 | ABCB11 (0.53) | ABCB11PTGDR2BACE1DDR1 | |
| SCHEMBL3839887 | 0.78 | ABCB11 (0.48) | ABCB11PTGDR2BACE1 | |
| SCHEMBL5430463 | 0.75 | PTGDR2 (0.60) | ABCB11PTGDR2DDR1 | |
| SCHEMBL1753566 | 0.73 | PTGDR2 (0.72) | ABCB11PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784388-B3 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2012-09-05 | — | — | EP | disclosed |
| EP-1784388-B1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2009-11-04 | — | — | EP | disclosed |
| EP-1784388-A1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | AstraZeneca AB (SE) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006021759-A1 | BIPHENYLOXYACETIC ACID DERIVATIVES FOR THE TREATMENT OF RESPIRATORY DISEASE | ASTRAZENECA AB (SE) | 2006-03-02 | — | — | WO | disclosed |