Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574488 | 0.77 | — | — | |
| SCHEMBL5949967 | 0.74 | — | — | |
| SCHEMBL9333404 | 0.73 | TSHR (0.40) | TSHRALDH1A1TDP1 | |
| SCHEMBL2400020 | 0.73 | TSHR (0.32) | TSHR | |
| SCHEMBL9308453 | 0.70 | — | — | |
| SCHEMBL9289438 | 0.70 | — | — | |
| SCHEMBL10904108 | 0.70 | — | — | |
| SCHEMBL5702641 | 0.70 | TSHR (0.37) | TSHR | |
| SCHEMBL11020010 | 0.69 | CYP3A4 (0.31) | — | |
| SCHEMBL472193 | 0.67 | TSHR (0.44) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2111393-A2 | PROCESS FOR THE SYNTHESIS OF DIAMINOPYRIDINES FROM GLUTARONITRILES | E. I. Du Pont de Nemours and Company (US) | 2009-10-28 | — | — | EP | disclosed |
| CN-101563325-A | Process for the synthesis of diaminopyridines from glutaronitriles | DU PONT (US) | 2009-10-21 | — | — | CN | disclosed |
| WO-2008082509-A2 | PROCESS FOR THE SYNTHESIS OF DIAMINOPYRIDINES FROM GLUTARONITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |