Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333397 | 0.91 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL5702641 | 0.91 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL27574488 | 0.85 | — | — | |
| SCHEMBL23388971 | 0.83 | TSHR (0.42) | TSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL3456781 | 0.77 | TSHR (0.37) | TSHRDNM1 | |
| SCHEMBL2232189 | 0.76 | DNM1 (0.33) | TSHRDNM1ALDH1A1TDP1 | |
| SCHEMBL28162619 | 0.76 | TSHR (0.36) | TSHRDNM1 | |
| SCHEMBL9308453 | 0.74 | — | — | |
| SCHEMBL3838745 | 0.73 | TSHR (0.48) | TSHRALDH1A1TDP1 | |
| SCHEMBL3457116 | 0.73 | DNM1 (0.37) | TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592488-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | INSTITUTO GENTILI S.P.A. (IT) | 1994-04-20 | — | — | EP | disclosed |
| WO-1993000348-A1 | DIMETHYLAMINO-HYDROXY-ALKAN DIPHOSPHONIC ACIDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ISTITUTO GENTILI S.P.A. (IT) | 1993-01-07 | — | — | WO | disclosed |