Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7103925 | 1.00 | DNM1 (0.57) | DNM1MEN1KMT2ATP53MAPK1 | |
| Acetic Acid SCHEMBL27916249 | 0.95 | DNM1 (0.55) | DNM1MEN1KMT2ATP53MAPK1 | |
| Tetrabuthylammonium SCHEMBL3646008 | 0.94 | DNM1 (0.49) | DNM1MEN1KMT2ATP53MAPK1 | |
| Acetic Acid SCHEMBL6014071 | 0.94 | DNM1 (0.47) | DNM1MEN1KMT2ATP53MAPK1 | |
| Bicarbonate SCHEMBL10523062 | 0.91 | DNM1 (0.57) | DNM1MEN1KMT2ATP53MAPK1 | |
| Bicarbonate SCHEMBL28308088 | 0.89 | DNM1 (0.49) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL612163 | 0.88 | DNM1 (0.70) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL15889308 | 0.88 | DNM1 (0.70) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL15889245 | 0.88 | DNM1 (0.70) | DNM1MEN1KMT2ATP53MAPK1 | |
| SCHEMBL15889250 | 0.88 | DNM1 (0.70) | DNM1MEN1KMT2ATP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| EP-1682609-B1 | METHOD OF MODIFYING A FLUOROPOLYMER AND ARTICLES THEREBY | 3M INNOVATIVE PROPERTIES CO (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2014703-B1 | Process of preparing a composite article | 3M INNOVATIVE PROPERTIES CO (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-2014703-A1 | Method of modifying a fluoropolymer and articles thereby | 3M Innovative Properties Company (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1453896-B1 | PROCESS FOR MODIFYING A POLYMERIC SURFACE | 3M INNOVATIVE PROPERTIES CO (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-1461376-B1 | IMPROVED PROCESS FOR MODIFYING A POLYMERIC SURFACE | 3M INNOVATIVE PROPERTIES CO (US) | 2006-12-20 | — | — | EP | disclosed |
| US-7140413-B2 | Method of modifying a fluoropolymer and articles thereby | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-11-28 | — | — | US | disclosed |
| EP-1682609-A1 | METHOD OF MODIFYING A FLUOROPOLYMER AND ARTICLES THEREBY | 3M Innovative Properties Company (US) | 2006-07-26 | — | — | EP | disclosed |
| US-20060029812-A1 | Method of modifying a fluoropolymer and articles thereby | 3M INNOVATIVE PROPERTIES COMPANY | 2006-02-09 | — | — | US | disclosed |
| EP-0921155-B1 | FLUORORUBBER COATING COMPOSITION | DAIKIN IND LTD (JP) | 2003-05-02 | — | — | EP | disclosed |
| EP-0574319-B1 | Fluoroelastomer coating composition | DYNEON LLC (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0670868-B1 | FLUORORUBBER COATING COMPOSITION | MINNESOTA MINING & MFG (US) | 1997-01-22 | — | — | EP | disclosed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | disclosed |
| EP-0670868-A1 | FLUORORUBBER COATING COMPOSITION. | MINNESOTA MINING & MFG (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012580-A1 | FLUORORUBBER COATING COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| US-4399272-A | COPOLYMERIZING FORMALDEHYDE AND AN ALKYLENE OXIDE OR CYCLIC FORMAL USING A LEWIS ACID AND ANIONIC CATALYST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-08-16 | — | — | US | disclosed |