SCHEMBL3838871

SCHEMBL3838871

CC(C)(C)OC(=O)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.63
CA1 P00915 1/20 0.63
CA7 P43166 1/20 0.63
CA14 Q9ULX7 1/20 0.63
NAMPT P43490 2/20 0.58
ATM Q13315 1/20 0.57
CTSK P43235 1/20 0.56
IDO1 P14902 1/20 0.56
RIPK1 Q13546 1/20 0.56
HDAC1 Q13547 1/20 0.55
KDM4A O75164 1/20 0.55
SYK P43405 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 1/20 0.53
RAB9A P51151 1/20 0.53
AKT1 P31749 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7982271 0.97 CA12 (0.60) CA12CA1CA7CA14NAMPT
Propionic Acid SCHEMBL8139542 0.94 CA12 (0.61) CA12CA1CA7CA14NAMPT
Acetic Acid Methyl Ester SCHEMBL8138995 0.94 CA12 (0.57) CA12CA1CA7CA14NAMPT
Acetaldehyde SCHEMBL3344850 0.94 CA12 (0.57) CA12CA1CA7CA14NAMPT
Propionamide SCHEMBL8144889 0.91 CA12 (0.55) CA12CA1CA7CA14NAMPT
SCHEMBL28466072 0.91 SYK (0.56) CA12CA1CA7CA14NAMPT
SCHEMBL3180689 0.91 L3MBTL1 (0.61) CA12CA1CA7CA14NAMPT
SCHEMBL1691047 0.90 HDAC1 (0.67) CA12CA1CA7CA14NAMPT
SCHEMBL185365 0.89 ATM (0.55) CA12CA1CA7CA14NAMPT
SCHEMBL14485285 0.89 SYK (0.62) CA12CA1CA7CA14NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551326-A Foamable composition based on perfluororubber and preparation method thereof 上海芯密科技有限公司 2024-02-13 CN claimed
CN-101429194-B Process for the preparation of tryptase inhibitors AVENTIS PHARMACEUTICALS, INC. (US) 2011-12-14 CN claimed
CN-101429194-A Process for the preparation of tryptase inhibitors AVENTIS PHARMA INC (US) 2009-05-13 CN claimed
CN-1950362-A Preparation method of tryptase inhibitor AVENTIS PHARMA INC (US) 2007-04-18 CN claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed
EP-1060178-B1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES PFIZER (US) 2003-09-03 EP claimed
US-6610707-B1 Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. PFIZER INC. 2003-08-26 US claimed
EP-1060178-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES PFIZER INC. (US) 2000-12-20 EP claimed
WO-1999045006-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES PFIZER INC. (US) 1999-09-10 WO claimed
US-5290957-A Process for the stereoselective preparation of phenylisoserine derivatives used in making taxols RHONE POULENC RORER S.A. (FR) 1994-03-01 US claimed
US-4008231-A Preparation of 3-methoxymethylcephalosporins ELI LILLY AND COMPANY (US) 1977-02-15 US claimed
WO-2025074096-A1 P97 (VCP) ATPASE INHIBITORS Turbine Simulated Cell Technologies Ltd (GB) 2025-04-10 WO disclosed
CN-119654324-A Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same 株式会社次代生物科学 2025-03-18 CN disclosed
CN-119013277-A TYK2 degrading agent and application thereof 凯麦拉医疗公司 2024-11-22 CN disclosed
US-12089618-B2 Rapid fermentation method for shrimp paste based on combined strain fortification JIANGSU UNIVERSITY (CN) 2024-09-17 US disclosed
CN-1030237-A BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMA CO LTD (JP) 1989-01-11 CN disclosed
EP-0287951-A2 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-10-26 EP disclosed
CN-88100500-A NOVEL POLYAMINE DERIVATIVES 1988-09-07 CN disclosed
US-4725680-A AMINATION, CLEAVAGE, NEUTRALIZATION SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1988-02-16 US disclosed
US-4008231-A Preparation of 3-methoxymethylcephalosporins ELI LILLY AND COMPANY (US) 1977-02-15 US disclosed