Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148270 | 0.86 | IDO1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL7753169 | 0.86 | IDO1 (0.44) | CA1CA2CA7CA9CA12 | |
| SCHEMBL11551016 | 0.79 | MCHR1 (0.36) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL2232272 | 0.79 | CYP2A6 (0.41) | ALDH1A1LMNAMAPTKDM4ECYP2A6 | |
| SCHEMBL7200087 | 0.79 | — | — | |
| SCHEMBL9739241 | 0.77 | MAPT (0.36) | CA1CA2CA7CA9CA12 | |
| SCHEMBL4308681 | 0.77 | SMN1; SMN2 (0.40) | CA1CA2CA7CA9CA12 | |
| SCHEMBL8748364 | 0.77 | MAPK1 (0.42) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL6050120 | 0.77 | CYP2A6 (0.44) | CYP2A6 | |
| SCHEMBL2253192 | 0.77 | NQO1 (0.47) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808045-B | Method for synthesizing chiral seven-element cyclic sulfonamide through organic catalysis | 中国科学院大连化学物理研究所 | 2022-07-08 | — | — | CN | claimed |
| US-9834537-B2 | Compounds as chloride channel blocking agent | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-12-05 | — | — | US | claimed |
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-05-28 | — | — | US | claimed |
| US-6509426-B2 | Dichloro(1,1'-dimethylsilylenebis(2-methyl-4-(4-methoxyphenyl) -4H-azulenyl))zirconium, for example; can produce polyolefin with high molecular weight and high melting point for extrusion or injection moldability | JAPAN POLYCHEM CORPORATION (JP) | 2003-01-21 | — | — | US | claimed |
| US-5750469-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | claimed |
| EP-0508220-B1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE AG (DE) | 1995-07-26 | — | — | EP | claimed |
| US-5274098-A | Amidinophenylalanine derivatives, process for their preparation, their use and compositions containing them | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | claimed |
| EP-0508220-A1 | Derivatives of amindinophenylalanine, procedure for their preparation, their utilisation and compositions comprising them | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-10-14 | — | — | EP | claimed |
| US-4104392-A | N2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1978-08-01 | — | — | US | claimed |
| US-4096255-A | ANTICOAGULANTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-20 | — | — | US | claimed |
| US-4071621-A | N2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-31 | — | — | US | claimed |
| US-4069318-A | INHIBITION AND SUPPRESSION OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1978-01-17 | — | — | US | claimed |
| US-4066758-A | ANTITHROMBOTIC | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-01-03 | — | — | US | claimed |
| US-4055651-A | THROMBOSIS INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-10-25 | — | — | US | claimed |
| US-4055636-A | THROMBOSIS INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-10-25 | — | — | US | claimed |
| US-4046876-A | THROMBIN INHIBITORS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-09-06 | — | — | US | claimed |
| US-4041156-A | ANTITHROMBOGENIC AGENTS | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1977-08-09 | — | — | US | claimed |
| US-4036955-A | TREATMENT OF THROMBOSIS | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-07-19 | — | — | US | claimed |
| US-4018915-A | ANTITHROMBOTIC | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-04-19 | — | — | US | claimed |
| US-4018913-A | N2 -alkoxynaphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-04-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150148550-A1 | NOVEL COMPOUNDS AS CHLORIDE CHANNEL BLOCKING AGENT | CACNB2, CACNB1, CACNB4 | CA1 656/4885CA2 151/4885CA7 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.