Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308681 | 0.81 | SMN1; SMN2 (0.40) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL8904048 | 0.80 | NSD2 (0.36) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL383902 | 0.77 | CA1 (0.41) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL4307895 | 0.76 | CYP1A2 (0.45) | ALDH1A1HPGDTSHRL3MBTL1HSD17B10 | |
| SCHEMBL28957180 | 0.76 | CA1 (0.39) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL9740648 | 0.75 | TDP1 (0.43) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL2411016 | 0.72 | CYP1A2 (0.32) | — | |
| SCHEMBL1193385 | 0.71 | EP300 (0.47) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL148270 | 0.71 | IDO1 (0.44) | MAPTIDO1EP300KAT8NQO1 | |
| SCHEMBL7753169 | 0.71 | IDO1 (0.44) | MAPTIDO1EP300KAT8NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |