Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839885 | 0.90 | DHODH (0.61) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL10861496 | 0.80 | DHODH (0.70) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL10863692 | 0.79 | DHODH (0.90) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL5664134 | 0.78 | DHODH (0.39) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL18120678 | 0.76 | DHODH (1.00) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL3836341 | 0.76 | DHODH (0.61) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL3894378 | 0.75 | DHODH (0.63) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL5046712 | 0.75 | DHODH (1.00) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL14341439 | 0.75 | DHODH (0.67) | DHODHNPSR1KDM4EMAPTKMT2A | |
| SCHEMBL10862238 | 0.75 | DHODH (0.67) | DHODHNPSR1KDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833830-B1 | QUINOLINE DERIVATIVE, USE AND PRODUCTION THEREOF, AND DRUG CONTAINING THE SAME | BAYER SCHERING PHARMA AG (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-20060167035-A1 | Quinoline derivative, its use, production and pharmaceutical agents containing the latter | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167035-A1 | Quinoline derivative, its use, production and pharmaceutical agents containing the latter | NQO2, RECQL, XDH | DHODH 1724/4885NPSR1 533/4885KDM4E 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.