Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 14/20 | 0.67 |
| ▸ | CPT1B | Q92523 | 14/20 | 0.67 |
| ▸ | CPT2 | P23786 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903690 | 0.92 | CPT1A (0.77) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3840063 | 0.90 | CPT1A (0.75) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2903680 | 0.89 | CPT1A (0.64) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3837067 | 0.88 | CPT1A (0.84) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2905345 | 0.80 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL2906465 | 0.80 | CPT1A (0.85) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2898003 | 0.79 | CPT1A (0.68) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3837062 | 0.79 | CPT1A (0.97) | CPT1ACPT1BCPT2 | |
| SCHEMBL3945257 | 0.78 | CPT1A (0.85) | CPT1ACPT1BCPT2 | |
| SCHEMBL2906127 | 0.77 | CPT1A (0.66) | CPT1ACPT1BCPT2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097373-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074692-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | disclosed |