Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14554032 | 0.95 | BCHE (0.66) | BCHESMN1; SMN2 | |
| SCHEMBL14217826 | 0.95 | BCHE (0.66) | BCHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28558935 | 0.94 | BCHE (0.64) | BCHESMN1; SMN2 | |
| SCHEMBL7328973 | 0.91 | BCHE (0.73) | BCHE | |
| SCHEMBL31549855 | 0.89 | BCHE (0.76) | BCHES1PR5 | |
| SCHEMBL31549856 | 0.89 | BCHE (0.76) | BCHES1PR5 | |
| SCHEMBL31549848 | 0.89 | BCHE (0.76) | BCHES1PR5 | |
| SCHEMBL31549857 | 0.89 | BCHE (0.76) | BCHES1PR5 | |
| SCHEMBL3844246 | 0.86 | ALDH1A1 (0.53) | BCHESMN1; SMN2 | |
| SCHEMBL3842797 | 0.86 | ALDH1A1 (0.55) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931341-B1 | 1H-INDOLE-PYRIDINECARBOXAMIDE AND 1H-INDOLE-PIPERIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS TYROSINE HYDROXYLASE INDUCERS | SERVIER LAB (FR) | 2009-11-04 | — | — | EP | disclosed |