Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.52 |
| ▸ | CTSK | P43235 | 11/20 | 0.52 |
| ▸ | CTSL | P07711 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010225 | 0.78 | CTSS (0.81) | CTSSCTSKCTSL | |
| SCHEMBL3010222 | 0.78 | CTSS (0.81) | CTSSCTSKCTSL | |
| SCHEMBL3010218 | 0.78 | CTSS (0.81) | CTSSCTSKCTSL | |
| SCHEMBL3835679 | 0.69 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3839931 | 0.68 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020642 | 0.67 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020641 | 0.67 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL3020639 | 0.67 | CTSS (1.00) | CTSSCTSKCTSL | |
| SCHEMBL4798882 | 0.66 | CTSS (0.48) | CTSSCTSKCTSL | |
| SCHEMBL13211446 | 0.65 | CTSS (0.76) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-B1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2009-10-14 | — | — | EP | disclosed |