Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.74 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840560 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3840564 | 1.00 | ADRB2 (0.74) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3843146 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3843666 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3843145 | 0.85 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3196551 | 0.84 | ADRB2 (0.87) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838435 | 0.84 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838432 | 0.84 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838557 | 0.84 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3842096 | 0.84 | ADRB2 (1.00) | ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641465-B1 | COMBINATIONS OF AN ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONIST AND A CORTICOSTEROID | THERAVANCE INC (US) | 2009-11-04 | — | — | EP | claimed |
| EP-1446379-B1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-04-29 | — | — | EP | claimed |