Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 6/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599881 | 0.89 | ST6GAL1 (0.40) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL17599856 | 0.88 | ST6GAL1 (0.42) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL383446 | 0.84 | PDE4D (0.46) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL3793139 | 0.83 | PDE4D (0.40) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL5150771 | 0.82 | NT5E (0.51) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL26647620 | 0.82 | TYMP (0.54) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1318619 | 0.82 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL1317526 | 0.82 | NT5E (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL5318031 | 0.81 | ST6GAL1 (0.45) | ST6GAL1NT5ELMNATHRBMTOR | |
| SCHEMBL4458009 | 0.78 | ST6GAL1 (0.42) | ST6GAL1NT5ELMNATHRBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010108140-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2010-09-23 | — | — | WO | disclosed |