Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17958819 | 1.00 | KCNH2 (0.55) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4244081 | 1.00 | KCNH2 (0.55) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5298152 | 0.98 | KCNH2 (0.56) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5298170 | 0.98 | KCNH2 (0.56) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5283071 | 0.98 | KCNH2 (0.56) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5296480 | 0.98 | KCNH2 (0.56) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL1168958 | 0.98 | KCNH2 (0.56) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL11544841 | 0.96 | KCNH2 (0.55) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL8983464 | 0.96 | KCNH2 (0.55) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 | |
| Bromide SCHEMBL8431151 | 0.96 | KCNH2 (0.55) | KCNH2MEN1MAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250381253-A1 | MUTANASES AND ORAL CARE COMPOSITIONS COMPRISING SAME | NOVOZYMES A/S (DK) | 2025-12-18 | — | — | US | disclosed |
| US-20250161187-A1 | ORAL CARE COMPOSITION COMPRISING ENZYMES | NOVOZYMES A/S (DK) | 2025-05-22 | — | — | US | disclosed |
| EP-3664776-B1 | APTAMERS FOR CONSUMER PRODUCT COMPOSITIONS | PROCTER & GAMBLE (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025093061-A1 | COMPLEX FOR BLOCKING DENTINAL TUBULES, REAGENT FOR TREATING DENTIN HYPERSENSITIVITY, AND USE THEREOF | 安徽医科大学 | 2025-05-08 | — | — | WO | disclosed |
| EP-4547210-A1 | MUTANASES AND ORAL CARE COMPOSITIONS COMPRISING SAME | Novozymes A/S (DK) | 2025-05-07 | — | — | EP | disclosed |
| EP-4482458-A1 | ORAL CARE COMPOSITION COMPRISING ENZYMES | Novozymes A/S (DK) | 2025-01-01 | — | — | EP | disclosed |
| EP-4447989-A1 | ORAL CARE COMPOSITION COMPRISING ENZYMES | Novozymes A/S (DK) | 2024-10-23 | — | — | EP | disclosed |
| WO-2024175631-A1 | ORAL CARE COMPOSITION COMPRISING INVERTASE | NOVOZYMES A/S (DK) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024003143-A1 | MUTANASES AND ORAL CARE COMPOSITIONS COMPRISING SAME | NOVOZYMES A/S (DK) | 2024-01-04 | — | — | WO | disclosed |
| US-20230332124-A1 | ORAL CARE COMPOSITION COMPRISING A FRUCTANASE | NOVOZYMES A/S (DK) | 2023-10-19 | — | — | US | disclosed |
| EP-0363748-B1 | Oral compositions | PROCTER & GAMBLE (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0370296-B1 | Chewing gum | PROCTER & GAMBLE (US) | 1994-01-19 | — | — | EP | disclosed |
| EP-0181179-B1 | ANTIMICROBIAL LOZENGES | THE PROCTER & GAMBLE COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5017385-A | Organoleptic | THE PROCTER & GAMBLE COMPANY (US) | 1991-05-21 | — | — | US | disclosed |
| US-4994262-A | Mouthwashes or dentifrices containing cationic surfactant microbiocides and salts of benzoic or phthalic acids | THE PROCTER & GAMBLE COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0370296-A2 | Chewing gum | THE PROCTER & GAMBLE COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0363748-A2 | Oral compositions | THE PROCTER & GAMBLE COMPANY (US) | 1990-04-18 | — | — | EP | disclosed |
| US-4765984-A | ALGINATE CROSSLINKED WITH CALCIUM, FLAVOR, WATER, HUMECTANT, VEGETABLE OIL | COLGATE-PALMOLIVE COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| US-4624849-A | CATIONIC MICROBIAL ANTIPLAQUE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1986-11-25 | — | — | US | disclosed |
| EP-0181179-A2 | Antimicrobial lozenges | THE PROCTER & GAMBLE COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |