SCHEMBL384145

SCHEMBL384145

Nc1ncnc2c1ncn2CC(CF)OCP(=O)(O)O

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.72
FGFR1 P11362 1/20 0.60
SLC22A6 Q4U2R8 1/20 0.60
HPRT1 P00492 5/20 0.54
ADORA2A P29274 2/20 0.52
ADORA1 P30542 1/20 0.52
ALDH1A1 P00352 1/20 0.52
CYP2D6 P10635 6/20 0.52
AHCY P23526 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2928584 1.00 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL9190527 1.00 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL14665386 0.91 CYP3A4 (0.63) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL14665374 0.91 CYP3A4 (0.63) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL29437221 0.90 CYP3A4 (0.73) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL66563 0.90 CYP3A4 (0.73) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL385752 0.90 CYP3A4 (0.73) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL31414425 0.88 CYP3A4 (0.71) CYP3A4FGFR1SLC22A6HPRT1ADORA2A
SCHEMBL19994970 0.87 CYP3A4 (0.57) CYP3A4FGFR1SLC22A6ADORA2AADORA1
SCHEMBL19994967 0.87 CYP3A4 (0.57) CYP3A4FGFR1SLC22A6ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118530282-A Improvement of liver-targeting cyclic phosphate prodrug structure 广州麦克斯药物研究有限公司 2024-08-23 CN claimed
CN-112463529-B Temperature control method and device of solid-state memory and related components 苏州浪潮智能科技有限公司 2023-01-10 CN claimed
EP-2846788-A1 USE OF COMPOUNDS FOR THE TREATMENT OF PAIN Akron Molecules AG (AT) 2015-03-18 EP claimed
WO-2013167743-A1 USE OF COMPOUNDS FOR THE TREATMENT OF PAIN AKRON MOLECULES GMBH (AT) 2013-11-14 WO claimed
US-7205404-B1 Phosphorus-containing prodrugs METABASIS THERAPEUTICS, INC. (US) 2007-04-17 US claimed
EP-1165570-B9 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS INC (US) 2007-02-21 EP claimed
EP-1165570-B1 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS INC (US) 2006-08-23 EP claimed
EP-0533833-B1 PHOSPHOROUS PRODUGS GLAZIER ARNOLD (US) 1995-12-20 EP claimed
JP-6206888-A None JP disclosed
US-12378306-B2 Anti-fungal VHH antibodies Biotalys NV (BE) 2025-08-05 US disclosed
WO-2025133390-A1 ANTI-FUNGAL VHH ANTIBODIES Biotalys NV (BE) 2025-06-26 WO disclosed
US-20250206811-A1 ANTI-FUNGAL VHH ANTIBODIES Biotalys NV (BE) 2025-06-26 US disclosed
EP-4574981-A1 ANTI-FUNGAL VHH ANTIBODIES Biotalys NV (BE) 2025-06-25 EP disclosed
WO-2025128741-A1 OCTADECANOID COMPOSITIONS AND METHODS OF ACTIVATING MUCOSAL REPAIR PATHWAYS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-06-19 WO disclosed
US-5352786-A Di(2-propyl)esters of 1-fluoro-2-phosphonomethoxy-3-P-to-luenesulfonyloxypropanes, their producing and utilization INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1994-10-04 US disclosed
JP-H06206888-A N-(3-FLUORO-2-PHOSPHONYLMETHOXYPROPYL) DERIVATIVE OF PURINE AND PYRIMIDINE HETEROCYCLIC BASES, ITS PREPARATION AND USE AKAD VED CESKE REPUBLIKY 1994-07-26 JP disclosed
EP-0540707-A1 Di(2-PROPYL)ESTERS OF 1-FLUORO-2-PHOSPHONOMETHOXY-3-P-TOLUENESULFONYLOXYPROPANES, THEIR PRODUCING AND UTILIZATION. CESKOSLOVENSKA AKADEMIE VED (CS) 1993-05-12 EP disclosed
WO-1992020692-A1 DI(2-PROPYL)ESTERS OF 1-FLUORO-2-PHOSPHONOMETHOXY-3-P-TOLUENESULFONYLOXYPROPANES, THEIR PRODUCING AND UTILIZATION GILEAD SCIENCES, INC. (US) 1992-11-26 WO disclosed
WO-1992020691-A1 Di(2-PROPYL)ESTERS OF 1-FLUORO-2-PHOSPHONOMETHOXY-3-P-TOLUENESULFONYLOXYPROPANES, THEIR PRODUCING AND UTILIZATION C^¿ESKOSLOVENSKÁ AKADEMIE VE^¿D (CS) 1992-11-26 WO disclosed
EP-0454427-A1 Antiretroviral bases Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic (CZ) 1991-10-30 EP disclosed