SCHEMBL66563

SCHEMBL66563

Nc1ncnc2c1ncn2CC(CO)OCP(=O)(O)O

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.73
FGFR1 P11362 3/20 0.61
SLC22A6 Q4U2R8 1/20 0.61
ADORA2A P29274 3/20 0.58
AHCY P23526 2/20 0.58
ADORA1 P30542 2/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP2D6 P10635 6/20 0.52
HPRT1 P00492 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL385752 1.00 CYP3A4 (0.73) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL29437221 1.00 CYP3A4 (0.73) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL10047654 0.91 CYP3A4 (0.64) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL14669069 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL2556627 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL2556635 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL2928584 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL12354858 0.90 CYP3A4 (0.62) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL9190527 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY
SCHEMBL384145 0.90 CYP3A4 (0.72) CYP3A4FGFR1SLC22A6ADORA2AAHCY

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022013813-A1 COMPOUND AND PHARMACEUTICAL COMPOSITION FOR USE IN TREATING HUMAN CYTOMEGALOVIRUS INFECTIONS UNIVERSITÀ DEGLI STUDI DI PADOVA (IT) 2022-01-20 WO claimed
US-20160000937-A1 MODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER THERAPY ALT SOLUTIONS, INC. 2016-01-07 US claimed
US-20140065072-A1 Modulation of Telomere Length in Telomerase Positive Cells and Cancer Therapy ALT SOLUTIONS INC. (US) 2014-03-06 US claimed
US-8580753-B2 Modulation of telomere length in telomerase positive cells and cancer therapy ALT SOLUTIONS INC. (US) 2013-11-12 US claimed
US-20120107863-A1 MODULATION OF TELOMERE LENGTH IN TELOMERASE POSITIVE CELLS AND CANCER THERAPY ALT SOLUTIONS INC. (US) 2012-05-03 US claimed
US-8097595-B2 Modulation of telomere length in telomerase positive cells and cancer therapy ALT SOLUTIONS, INC. (US) 2012-01-17 US claimed
JP-2012500104-A 2012-01-05 JP claimed
EP-2320991-A2 DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT Third Rock Ventures (US) 2011-05-18 EP claimed
WO-2010022252-A2 DEVICE AND METHOD FOR DRUG EVALUATION AND LOCAL TREATMENT THIRD ROCK VENTURES (US) 2010-02-25 WO claimed
EP-1165570-B1 NOVEL PHOSPHORUS-CONTAINING PRODRUGS METABASIS THERAPEUTICS INC (US) 2006-08-23 EP claimed
US-6964968-B2 Method for the treatment or prevention of viral infection using nucleoside analogues SHIRE BIOCHEM, INC. (CA) 2005-11-15 US claimed
US-6583149-B1 2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-Dioxolane BIOCHEM PHARMA INC. (CA) 2003-06-24 US claimed
US-20250352777-A1 SUBMUCOSAL BIORESORBABLE DRUG ELUTING PLATFORM INTERSECT ENT INC (US) 2025-11-20 US disclosed
US-12403291-B2 Submucosal bioresorbable drug eluting platform INTERSECT ENT, INC. (US) 2025-09-02 US disclosed
US-12350274-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-08 US disclosed
EP-3791826-B1 SELF-EXPANDING DEVICES INTERSECT ENT INC (US) 2025-01-29 EP disclosed
US-20050180925-A1 powders has specific particle size distribution; increase bioavailability, prolonged therapeutic effect of the drug substance; aqueous suspension for inhalation; drug delivery method and device; comprise an antifungal agent, antibiotic or antiviral agent; fungus-induced rhinosinusitis DEY, L.P. 2005-08-18 US disclosed
US-20040209852-A1 Fluticasone powders has specific particle size distribution; increase bioavailability, prolonged therapeutic effect of the drug substance; aqueous suspension for inhalation; drug delivery method and device; comprise an antifungal agent, antibiotic or antiviral agent; fungus-induced rhinosinusitis MYLAN SPECIALTY L.P. 2004-10-21 US disclosed
US-6583149-B1 2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-Dioxolane BIOCHEM PHARMA INC. (CA) 2003-06-24 US disclosed
US-5874577-A Method for the preparing 9-12-(Diethoxyphosphonomethoxy)ethyl!adenine and analogues thereof MEDICHEM RESEARCH, INC. (US) 1999-02-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12350274-B2 Nucleotide analogs NUDT1, DUT, DPYD CYP3A4 3875/4885FGFR1 3575/4885SLC22A6 2557/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.