Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972019 | 0.70 | CYP1A2 (0.45) | KDM4EGAA | |
| SCHEMBL8127619 | 0.68 | PARP1 (0.39) | KDM4EGAA | |
| SCHEMBL3305453 | 0.65 | KDM4E (0.41) | CYP2A6KEAP1KDM4EGAAAXL | |
| SCHEMBL72252 | 0.64 | — | — | |
| SCHEMBL70450 | 0.63 | — | — | |
| SCHEMBL2464427 | 0.61 | DAO (0.53) | CYP2A6KEAP1KDM4EAXL | |
| SCHEMBL2356812 | 0.61 | CYP1A2 (0.42) | CYP2A6KDM4EGAA | |
| SCHEMBL14438044 | 0.61 | ADORA2A (0.36) | HPGDSCYP2A6KEAP1KDM4EGAA | |
| SCHEMBL2358946 | 0.61 | CYP1A2 (0.42) | CYP2A6KDM4EGAA | |
| SCHEMBL8120582 | 0.60 | ALDH1A1 (0.35) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | disclosed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | disclosed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | disclosed |