Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10556974 | 0.88 | CYP2C19 (0.45) | CYP1A2CYP2C19CYP3A4TSHRACHE | |
| SCHEMBL1969838 | 0.86 | CYP1A2 (0.58) | CYP1A2CYP2C19CYP3A4TSHRACHE | |
| SCHEMBL2883933 | 0.80 | PRMT5 (0.49) | CYP1A2CYP2C19CYP3A4TSHRMAPT | |
| SCHEMBL9385863 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP3A4TSHRACHE | |
| SCHEMBL1027225 | 0.79 | TSHR (0.51) | CYP1A2CYP2C19CYP3A4TSHRMAPT | |
| SCHEMBL11114800 | 0.77 | TSHR (0.55) | CYP1A2CYP2C19CYP3A4TSHRMAPT | |
| SCHEMBL10623825 | 0.77 | CA2 (0.57) | CYP1A2CYP2C19CYP3A4TSHRKMT2A | |
| SCHEMBL10560069 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP3A4TSHRACHE | |
| SCHEMBL6674437 | 0.74 | TSHR (0.59) | CYP1A2CYP2C19CYP3A4TSHRACHE | |
| Dinitrophenylene SCHEMBL28198017 | 0.74 | TSHR (0.56) | CYP1A2CYP2C19CYP3A4TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848691-B1 | PROCESS FOR THE PREPARATION OF INDOLONE DERIVATIVE | ALEMBIC LTD (IN) | 2009-11-11 | — | — | EP | claimed |