SCHEMBL384165

SCHEMBL384165

N[C@H]1CC[C@H](C(=O)O)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
PLG P00747 1/20 0.54
PLAT P00750 1/20 0.54
TSHR P16473 3/20 0.48
GABRP O00591 2/20 0.48
GABRD O14764 2/20 0.48
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRG2 P18507 2/20 0.48
GABRB3 P28472 2/20 0.48
GABRA5 P31644 2/20 0.48
GABRA3 P34903 2/20 0.48
GABRA2 P47869 2/20 0.48
GABRB2 P47870 2/20 0.48
GABRA4 P48169 2/20 0.48
GABRE P78334 2/20 0.48
GABRA6 Q16445 2/20 0.48
GABRG1 Q8N1C3 2/20 0.48
GABRG3 Q99928 2/20 0.48
GABRQ Q9UN88 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382975 1.00 LMNA (0.54) LMNAPLGPLATTSHRGABRP
SCHEMBL29265359 1.00 LMNA (0.54) LMNAPLGPLATTSHRGABRP
SCHEMBL218064 1.00 LMNA (0.54) LMNAPLGPLATTSHRGABRP
Hydrochloric Acid SCHEMBL3363679 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
SCHEMBL20581837 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
Hydrochloric Acid SCHEMBL384984 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
Hydrochloric Acid SCHEMBL420116 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
SCHEMBL15401674 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
SCHEMBL15401713 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP
Methane SCHEMBL28827281 0.97 LMNA (0.52) LMNAPLGPLATTSHRGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 751 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120213-A Synthesis method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-16 CN claimed
CN-116082192-A Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexane carboxylic acid 重庆医药高等专科学校 2023-05-09 CN claimed
CN-113402428-B Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof 重庆医药高等专科学校 2023-03-03 CN claimed
CN-112125565-B Concrete corrosion and rust inhibitor and preparation method thereof 中国石油天然气集团公司 2022-05-31 CN claimed
CN-113402428-A Preparation method of trans-4- (tert-butoxycarbonylamino) cyclohexanecarboxylic acid and intermediate thereof 重庆医药高等专科学校 2021-09-17 CN claimed
US-20210238183-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS SUMITOMO PHARMA AMERICA, INC. 2021-08-05 US claimed
CN-112125565-A Concrete corrosion and rust inhibitor and preparation method thereof 中国石油天然气集团公司 2020-12-25 CN claimed
EP-2516009-B1 SUBSTITUTED ISOQUINOLINONES AND QUINAZOLINONES NOVARTIS AG (CH) 2014-09-24 EP claimed
US-8357654-B2 Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2013-01-22 US claimed
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-07-22 US claimed
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-06-03 US claimed
EP-1828240-B1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CENTRE NAT RECH SCIENT (FR) 2009-07-29 EP claimed
US-5679640-A BINDING TO MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) E.G. HLA-DR'S, TO INHIBIT HLA-DR RESTRICTED T CELL ACTIVATION; AUTOIMMUNE DISEASES; ANTIARTHRITIC AGENTS CYTEL CORPORATION (US) 1997-10-21 US claimed
JP-57122062-A None JP disclosed
CN-122059854-A Guanidino cyclohexane derivative and preparation method and application thereof 安徽益普克医药科技发展有限公司 2026-05-19 CN disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
US-4309429-A NEUROLEPTIC, ANTIEMETIC KEFALAS A/S (DK) 1982-01-05 US disclosed
US-4285956-A NEUROLEPTIC AND ANTICHOLENERGIC AGENTS; PSYCHOLOGICAL DISORDERS INCLUDING SCHIZOPHRENIA; ANTIEMETIC AGENTS KEFALAS A/S (DK) 1981-08-25 US disclosed
US-4275209-A NEUROLEPTIC AND ANTIEMETIC ACTIVITY FOR TREATMENT OF PSYCHOLOGICAL DISORDERS KEFALAS A/S (DK) 1981-06-23 US disclosed
EP-0005607-A1 Xanthone and thioxanthone derivatives, their preparation and pharmaceutical compositions containing them KEFALAS A/S (DK) 1979-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100183642-A1 NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS CD40, CD40LG, TNFSF10 LMNA 1693/4885PLG 2292/4885PLAT 1182/4885
US-20210238183-A1 SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES AS PROTEIN KINASE INHIBITORS PIM1, PIM2, PIM3 LMNA 2351/4885PLG 2785/4885PLAT 1809/4885
US-20100136034-A1 NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS TNFRSF1A, TNFRSF9, CD40 LMNA 3111/4885PLG 2786/4885PLAT 2302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.