Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 20/20 | 0.58 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811087 | 0.91 | PDE7A (0.52) | PDE7APDE7BPDE4D | |
| SCHEMBL1813455 | 0.90 | PDE7A (0.60) | PDE7APDE7BPDE4D | |
| SCHEMBL1814067 | 0.89 | PDE7A (0.61) | PDE7APDE7BPDE4D | |
| SCHEMBL1815153 | 0.89 | PDE7A (0.61) | PDE7APDE7BPDE4D | |
| SCHEMBL1815873 | 0.89 | PDE7A (0.61) | PDE7APDE7BPDE4D | |
| SCHEMBL1809916 | 0.88 | PDE7A (0.60) | PDE7APDE7BPDE4D | |
| SCHEMBL1817916 | 0.88 | PDE7A (0.59) | PDE7APDE7BPDE4D | |
| SCHEMBL1813868 | 0.86 | PDE7A (0.57) | PDE7APDE7BPDE4D | |
| SCHEMBL1810062 | 0.85 | PDE7A (0.56) | PDE7APDE7BPDE4D | |
| SCHEMBL5230256 | 0.85 | PDE7A (0.69) | PDE7APDE7BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4275752-A2 | TREATMENT OF ADDICTION AND IMPULSE-CONTROL DISORDERS USING PDE7 INHIBITORS | Omeros Corporation (US) | 2023-11-15 | — | — | EP | disclosed |
| US-11207275-B2 | Treatment of addiction and impulse-control disorders using PDE7 inhibitors | OMEROS CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| US-20190183824-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION | 2019-06-20 | — | — | US | disclosed |
| US-20190134055-A1 | Treatment of Addiction and Impulse-control Disorders Using PDE7 Inhibitors | OMEROS CORPORATION | 2019-05-09 | — | — | US | disclosed |
| EP-2427193-B1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORP (US) | 2018-07-11 | — | — | EP | disclosed |
| US-20160158247-A1 | Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors | OMEROS CORPORATION | 2016-06-09 | — | — | US | disclosed |
| US-20160158247-A1 | Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors | OMEROS CORPORATION | 2016-06-09 | — | — | US | disclosed |
| US-20160015715-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION | 2016-01-21 | — | — | US | disclosed |
| US-20160015715-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION | 2016-01-21 | — | — | US | disclosed |
| US-9220715-B2 | Treatment of addiction and impulse-control disorders using PDE7 inhibitors | OMEROS CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-7943624-B2 | Pyridinylpyrazolopyrimidinone derivatives as PDE 7 inhibitors | ASUBIO PHARMA CO. LTD. (JP) | 2011-05-17 | — | — | US | disclosed |
| US-20110091388-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110091388-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION (US) | 2011-04-21 | — | — | US | disclosed |
| EP-1636235-B1 | PYRIDINYLPYRAZOLOPYRIMIDINONE DERIVATIVES AS PDE 7 INHIBITORS | ASUBIO PHARMA CO LTD (JP) | 2009-10-14 | — | — | EP | disclosed |
| US-20080260643-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080260643-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| WO-2008119057-A2 | THE USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | OMEROS CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20070270419-A1 | PYRIDINYLPYRAZOLOPYRIMIDINONE DERIVATIVES AS PDE 7 INHIBITORS | ASUBIO PHARMA CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20070270419-A1 | PYRIDINYLPYRAZOLOPYRIMIDINONE DERIVATIVES AS PDE 7 INHIBITORS | ASUBIO PHARMA CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| US-20060128728-A1 | Pyridinylpyrazolopyrimidinone derivatives as pde 7 inhibitors | DAIICHI ASUBIO PHARMA CO., LTD (JP) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080260643-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | PARK7, PDE7B, PDE7A | PDE7A 3/4885PDE7B 2/4885PDE4D 16/4885 |
| US-20160158247-A1 | Treatment of Addiction and Impulse-Control Disorders Using PDE7 Inhibitors | PDE7B, PDE4C, PDE4A | PDE7A 10/4885PDE7B 1/4885PDE4D 7/4885 |
| US-20060128728-A1 | Pyridinylpyrazolopyrimidinone derivatives as pde 7 inhibitors | PDE7A, PDE5A, PDE3A | PDE7A 1/4885PDE7B 6/4885PDE4D 14/4885 |
| US-11207275-B2 | Treatment of addiction and impulse-control disorders using PDE7 inhibitors | PDE7B, PDE4C, PDE4A | PDE7A 10/4885PDE7B 1/4885PDE4D 7/4885 |
| US-20110091388-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | PARK7, PDE7B, PDE7A | PDE7A 3/4885PDE7B 2/4885PDE4D 16/4885 |
| US-20160015715-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | PARK7, PDE7B, PDE7A | PDE7A 3/4885PDE7B 2/4885PDE4D 16/4885 |
| US-20190134055-A1 | Treatment of Addiction and Impulse-control Disorders Using PDE7 Inhibitors | PDE7B, PDE4C, PDE4A | PDE7A 10/4885PDE7B 1/4885PDE4D 7/4885 |
| US-20070270419-A1 | PYRIDINYLPYRAZOLOPYRIMIDINONE DERIVATIVES AS PDE 7 INHIBITORS | PDE7A, PDE5A, PDE3A | PDE7A 1/4885PDE7B 6/4885PDE4D 15/4885 |
| US-20190183824-A1 | USE OF PDE7 INHIBITORS FOR THE TREATMENT OF MOVEMENT DISORDERS | PARK7, PDE7B, PDE7A | PDE7A 3/4885PDE7B 2/4885PDE4D 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.