Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.62 |
| ▸ | PPARG | P37231 | 13/20 | 0.62 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848511 | 0.97 | PPARA (0.64) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3285364 | 0.95 | PPARA (0.62) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3284572 | 0.91 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL3841400 | 0.91 | PPARA (0.49) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3843403 | 0.90 | PPARA (0.61) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3840968 | 0.89 | PPARA (0.48) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841188 | 0.88 | PPARA (0.60) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3285231 | 0.88 | PPARA (0.66) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3842008 | 0.88 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3843661 | 0.88 | PPARA (0.60) | PPARAPPARGPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |