Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3845359 | 0.96 | PPARA (0.50) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3869431 | 0.92 | PPARA (0.41) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3845812 | 0.91 | PPARA (0.45) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3842224 | 0.91 | PPARA (0.62) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3848511 | 0.90 | PPARA (0.64) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3842930 | 0.90 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3844620 | 0.89 | PPARA (0.48) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3848673 | 0.89 | PPARA (0.44) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3848566 | 0.89 | PPARA (0.39) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3840790 | 0.88 | PPARA (0.46) | PPARAPPARGPPARDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |