Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL5480449 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNASLC15A2TDP1PAOX | |
| Acetone SCHEMBL11150275 | 1.00 | ALDH1A1 (0.60) | ALDH1A1LMNASLC15A2TDP1PAOX | |
| SCHEMBL40380 | 0.96 | — | — | |
| Methyl Alcohol SCHEMBL5132978 | 0.93 | ALDH1A1 (0.60) | ALDH1A1LMNASLC15A2TDP1PAOX | |
| Methane SCHEMBL28805699 | 0.93 | — | — | |
| SCHEMBL29179529 | 0.93 | — | — | |
| SCHEMBL8105581 | 0.93 | — | — | |
| SCHEMBL129480 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL3762402 | 0.93 | — | — | |
| SCHEMBL3871414 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597262-B1 | SUBSTITUTED HETEROCYCLES | INTERMED DISCOVERY GMBH (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-1597262-A2 | SUBSTITUTED HETEROCYCLES | Bayer HealthCare AG (DE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004071382-A2 | SUBSTITUTED HETEROCYCLES | BAYER HEALTHCARE AG (DE) | 2004-08-26 | — | — | WO | disclosed |
| EP-0101186-B1 | N-METHYL 11-AZA-10-DEOXO-10-DIHYDROERYTHROMYCIN A, INTERMEDIATES THEREFOR AND PROCESSES FOR THEIR PREPARATION | PFIZER INC. (US) | 1986-11-05 | — | — | EP | disclosed |
| US-4474768-A | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor | PFIZER INC. (US) | 1984-10-02 | — | — | US | disclosed |