Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842432 | 0.96 | AGTR1 (0.52) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL3841024 | 0.93 | AGTR1 (0.45) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL3844498 | 0.88 | AGTR1 (0.49) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL668712 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL683727 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL668713 | 0.84 | AGTR1 (0.49) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL668336 | 0.83 | AGTR1 (0.57) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL668491 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL986792 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| Hydrochloric Acid SCHEMBL7305266 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136788-A1 | CANCER CELL TARGETING USING NANOPARTICLES | Bind Biosciences, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008121949-A1 | CANCER CELL TARGETING USING NANOPARTICLES | BIND BIOSCIENCES, INC. (US) | 2008-10-09 | — | — | WO | disclosed |