Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.41 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245504 | 0.79 | KDM1A (0.50) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL297140 | 0.79 | KDM1A (0.50) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL29196353 | 0.78 | KDM1A (0.47) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL30887515 | 0.78 | KDM1A (0.47) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL3842669 | 0.78 | KDM1A (0.47) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL14614919 | 0.77 | KDM1A (0.49) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| Hydrochloric Acid SCHEMBL20581296 | 0.77 | KDM1A (0.49) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL22501639 | 0.77 | TRPV1 (0.52) | KDM1AMAOAMAOBTRPV1DAO | |
| SCHEMBL13061262 | 0.76 | KDM1A (0.48) | KDM1AMAOAMAOBTRPV1TRPV4 | |
| SCHEMBL452178 | 0.76 | TRPV4 (0.52) | KDM1AMAOAMAOBTRPV1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979354-B1 | DIAZA-SPIRO-[4, 5]-DECANES USEFUL AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-11-11 | — | — | EP | disclosed |
| EP-2089034-A1 | NOVEL USES | Intra-Cellular Therapies, Inc. (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-2081431-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008070095-A1 | NOVEL USES | INTRA-CELLULAR THERAPIES, INC. (US) | 2008-06-12 | — | — | WO | disclosed |
| WO-2008063505-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2008-05-29 | — | — | WO | disclosed |