Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8582101 | 0.94 | MAOB (0.49) | MAOBAKR1C1LMNAHTTSLC6A2 | |
| SCHEMBL28268515 | 0.82 | MAOB (0.49) | MAOBAKR1C1HDAC4LMNAHTT | |
| SCHEMBL28505246 | 0.81 | MAOB (0.39) | MAOBAKR1C1HDAC4LMNAHTT | |
| SCHEMBL19817376 | 0.79 | AKR1C1 (0.40) | MAOBAKR1C1HDAC4SLC6A2SLC6A4 | |
| SCHEMBL16112661 | 0.78 | SLC6A3 (0.43) | MAOBAKR1C1HDAC4LMNAHTT | |
| Phosphoric Acid SCHEMBL3680815 | 0.76 | CHRM1 (0.38) | MAOBAKR1C1HDAC4SLC6A2SLC6A4 | |
| SCHEMBL4558511 | 0.75 | MEN1 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL4558510 | 0.75 | OPRL1 (0.39) | AKR1C1LMNASLC6A2SLC6A4 | |
| SCHEMBL5510286 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL9330906 | 0.72 | AKR1C1 (0.50) | AKR1C1HDAC4LMNAHTTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |