SCHEMBL3843069

SCHEMBL3843069

Oc1ccc(C23CC4CC(c5ccc(O)cc5O)(C2)CC(C25CC6CC(c7ccc(O)cc7O)(CC(c7ccc(O)cc7O)(C6)C2)C5)(C4)C3)c(O)c1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.35
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
GFER P55789 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX5AP P20292 1/20 0.33
HSP90AA1 P07900 1/20 0.31
LMNA P02545 1/20 0.31
ALOX12 P18054 1/20 0.31
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842486 0.97 CNR2 (0.34) CNR2MEN1POLBGAAGFER
SCHEMBL3846906 0.94 MEN1 (0.41) CNR2MEN1POLBGAAGFER
SCHEMBL3759906 0.93 CNR2 (0.38) CNR2MEN1POLBGAAGFER
SCHEMBL3849641 0.93 CNR2 (0.37) CNR2MEN1POLBGAAGFER
SCHEMBL3845041 0.85 KMT2A (0.40) CNR2MEN1POLBGAAGFER
SCHEMBL3845893 0.84 CNR2 (0.38) CNR2MEN1POLBGAAGFER
SCHEMBL2426368 0.83 KMT2A (0.43) CNR2MEN1POLBGAAGFER
SCHEMBL3844976 0.82 TYR (0.35) LMNAALOX12
SCHEMBL3759822 0.80 TYR (0.39) LMNAALOX12
SCHEMBL3764016 0.79 ALOX5AP (0.45) CNR2MEN1POLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed