SCHEMBL3846906

SCHEMBL3846906

Oc1ccc(C23CC4CC(c5ccc(O)cc5O)(C2)CC(C25CC6CC(CC(C6)C2)C5)(C4)C3)c(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
POLB P06746 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
CNR2 P34972 2/20 0.40
HSP90AA1 P07900 1/20 0.36
RARB P10826 3/20 0.35
THRB P10828 1/20 0.34
RECQL P46063 1/20 0.34
NR2E1 Q9Y466 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
RARA P10276 2/20 0.33
RARG P13631 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3843069 0.94 CNR2 (0.35) MEN1KMT2APOLBGAAGFER
SCHEMBL3849641 0.93 CNR2 (0.37) MEN1KMT2APOLBGAAGFER
SCHEMBL3842486 0.91 CNR2 (0.34) MEN1KMT2APOLBGAAGFER
SCHEMBL3759906 0.87 CNR2 (0.38) MEN1KMT2APOLBGAAGFER
SCHEMBL3845041 0.86 KMT2A (0.40) MEN1KMT2APOLBGAAGFER
SCHEMBL3845893 0.85 CNR2 (0.38) MEN1KMT2APOLBGAAGFER
SCHEMBL2426368 0.84 KMT2A (0.43) MEN1KMT2APOLBGAAGFER
SCHEMBL2420330 0.84 MEN1 (0.50) MEN1KMT2APOLBGAAGFER
SCHEMBL3841582 0.78 ESR1 (0.46) MEN1KMT2APOLBGAAGFER
SCHEMBL3844976 0.77 TYR (0.35) ALDH1A1CYP3A4ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed