Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842975 | 0.88 | ALDH1A1 (0.36) | POLBGAANPSR1 | |
| SCHEMBL4953953 | 0.87 | POLB (0.35) | POLBGAANPSR1 | |
| SCHEMBL36866 | 0.85 | POLB (0.41) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL37083 | 0.81 | POLB (0.39) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL720297 | 0.81 | POLB (0.43) | POLBGAANPSR1 | |
| SCHEMBL1803764 | 0.81 | POLB (0.39) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL1005389 | 0.81 | — | — | |
| SCHEMBL14507455 | 0.79 | ALDH1A1 (0.38) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL15962065 | 0.79 | POLB (0.38) | POLBGAANPSR1CHRM2CHRM4 | |
| SCHEMBL1198114 | 0.79 | TSHR (0.38) | POLBGAANPSR1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650214-B1 | Silicon compound | CHISSO CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-7375170-B2 | Organosilicon compound | CHISSO CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| EP-1849787-A1 | Organosilicon compound | Chisso Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1849788-A1 | Organosilicon compound | Chisso Corporation (JP) | 2007-10-31 | — | — | EP | disclosed |
| US-7256243-B2 | Silicon compound | CHISSO CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20060175684-A1 | Organosilicon compound | JNC PETROCHEMICAL CORPORATION (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1686133-A2 | Organosilicon compound | CHISSO CORPORATION (JP) | 2006-08-02 | — | — | EP | disclosed |
| EP-1650214-A2 | Silicon compound | CHISSO CORPORATION (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-20050250925-A1 | Silicon compound | JNC CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |