Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2037809 | 0.81 | BTK (0.46) | BTKLOXL2NAAAALOX5APFEN1 | |
| SCHEMBL13422264 | 0.79 | DHODH (0.53) | BTKLOXL2NAAAALOX5APFEN1 | |
| SCHEMBL7162849 | 0.79 | BTK (0.44) | BTKLOXL2NAAAALOX5APFEN1 | |
| SCHEMBL1450105 | 0.78 | MKNK1 (0.45) | DHODHELANE | |
| SCHEMBL27535828 | 0.77 | KDM4E (0.41) | FEN1 | |
| SCHEMBL28599020 | 0.77 | PTGS2 (0.49) | FEN1 | |
| SCHEMBL22116705 | 0.76 | ERN1 (0.42) | NPC1RAB9A | |
| SCHEMBL4056518 | 0.76 | DHODH (0.54) | BTKLOXL2NAAAALOX5APFEN1 | |
| SCHEMBL29501236 | 0.75 | BTK (0.50) | BTKLOXL2NAAAALOX5APFEN1 | |
| SCHEMBL7264367 | 0.75 | QPCT (0.48) | PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861365-B1 | N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2009-07-01 | — | — | EP | claimed |