Chloromethane

Chloromethane

SCHEMBL3843315

C=C(C)C(=O)OCC[N+](C)(C)C.CCl

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 6/20 0.61
CHRM1 P11229 6/20 0.61
CHRM3 P20309 6/20 0.61
CHRM2 P08172 5/20 0.57
CHRM4 P08173 5/20 0.57
CHRNB2 P17787 4/20 0.57
CHRNA4 P43681 4/20 0.57
CHRNA7 P36544 3/20 0.57
HTR1A P08908 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
PGR P06401 1/20 0.57
TBXA2R P21731 1/20 0.57
CHRNB4 P30926 1/20 0.57
CHRNA3 P32297 1/20 0.57
CHRNA10 Q9GZZ6 1/20 0.57
CHRNA9 Q9UGM1 1/20 0.57
GALR3 O60755 2/20 0.55
MAPT P10636 1/20 0.55
BLM P54132 1/20 0.55
GAA P10253 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL180003 0.96 CHRM5 (0.65) CHRM5CHRM1CHRM3CHRM2CHRM4
Hydrochloric Acid SCHEMBL30183040 0.96 CHRM5 (0.65) CHRM5CHRM1CHRM3CHRM2CHRM4
Hydrochloric Acid SCHEMBL15954 0.96 CHRM5 (0.65) CHRM5CHRM1CHRM3CHRM2CHRM4
Iodide SCHEMBL723953 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL31575073 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
SCHEMBL29649178 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
Ammonia Solution, Strong SCHEMBL468696 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
Bromide SCHEMBL366432 0.94 CHRM1 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
Hydrochloric Acid SCHEMBL9492830 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4
Hydrochloric Acid SCHEMBL28351837 0.94 CHRM5 (0.63) CHRM5CHRM1CHRM3CHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109219425-B Physiological articles 花王株式会社 2021-07-27 CN disclosed
EP-1500744-B9 PAPER-MAKING ADDITIVE AND METHOD FOR PRODUCING PAPER NOF CORP (JP) 2009-11-11 EP disclosed
EP-1500744-B1 PAPER-MAKING ADDITIVE AND METHOD FOR PRODUCING PAPER NOF CORP (JP) 2008-12-31 EP disclosed
US-7344621-B2 Paper additive composition and method for producing paper using the same NOF CORPORATION (JP) 2008-03-18 US disclosed
EP-1500744-A2 PAPER-MAKING ADDITIVE AND METHOD FOR PRODUCING PAPER NOF CORPORATION (JP) 2005-01-26 EP disclosed
US-20040188047-A1 Paper additive composition and method for producing paper using the same NOF CORPORATION 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040188047-A1 Paper additive composition and method for producing paper using the same PRMT1, SAT1, H1-0 CHRM5 872/4885CHRM1 324/4885CHRM3 2019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.