Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 known ✓ | P08912 | 6/20 | 0.63 |
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.63 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.63 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.59 |
| ▸ | CHRM4 known ✓ | P08173 | 5/20 | 0.59 |
| ▸ | CHRNA7 known ✓ | P36544 | 3/20 | 0.59 |
| ▸ | HTR1A known ✓ | P08908 | 2/20 | 0.59 |
| ▸ | CHRNB4 known ✓ | P30926 | 1/20 | 0.59 |
| ▸ | CHRNA3 known ✓ | P32297 | 1/20 | 0.59 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.57 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.54 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.54 |
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.59 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28351837 | 1.00 | CHRM5 (0.63) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL27653182 | 0.98 | CHRM5 (0.61) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL22128479 | 0.98 | CHRM5 (0.61) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL28918239 | 0.98 | CHRM5 (0.61) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL28832470 | 0.98 | CHRM5 (0.61) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL180003 | 0.98 | CHRM5 (0.65) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL30183040 | 0.98 | CHRM5 (0.65) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL15954 | 0.98 | CHRM5 (0.65) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL22128467 | 0.96 | CHRM5 (0.59) | CHRM5CHRM1CHRM3CHRM2CHRM4 | |
| Iodide SCHEMBL723953 | 0.96 | CHRM5 (0.63) | CHRM5CHRM1CHRM3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252629-A | Adhesives for dentin | GC CORPORATION (JP) | 1993-10-12 | — | — | US | claimed |
| WO-2021112219-A1 | SLUDGE DEHYDRATING AGENT AND SLUDGE DEHYDRATION METHOD | 栗田工業株式会社 | 2021-06-10 | — | — | WO | disclosed |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2017-09-28 | — | — | US | disclosed |
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | ALFA PARF GROUP S.P.A. (IT) | 2016-09-01 | — | — | US | disclosed |
| US-20160194209-A1 | BETA MOLECULAR SIEVE HAVING MULTI-LEVEL CHANNEL STRUCTURE AND PREPARATION METHOD THEREOF | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2016-07-07 | — | — | US | disclosed |
| EP-3037385-A1 | BETA MOLECULAR SIEVE HAVING MULTI-LEVEL CHANNEL STRUCTURE, AND PREPARATION METHOD THEREOF | Dalian Institute Of Chemical Physics, Chinese Academy of Sciences (CN) | 2016-06-29 | — | — | EP | disclosed |
| CN-105372963-A | charging roll, process cartridge, and image forming apparatus | CANON KK | 2016-03-02 | — | — | CN | disclosed |
| WO-2016026710-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | ALFA PARF GROUP S.P.A. (IT) | 2016-02-25 | — | — | WO | disclosed |
| US-5270055-A | Solid pharmaceutical sustained-release form | NORDMARK ARZNEIMITTEL GMBH (DE) | 1993-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250118-A1 | METHOD AND COMPOSITION TO REMODELLING KERATINIC FIBER | KRT18, FABP2, CPT1A | CHRM5 687/4885CHRM1 725/4885CHRM3 383/4885 |
| US-20170273881-A1 | COSMETIC COMPOSITION FOR KERATIN FIBRES | KRT18, GRHPR, CUTA | CHRM5 3088/4885CHRM1 4167/4885CHRM3 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.