SCHEMBL3843327

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3841013	0.85	TYR (0.47)	TYRHTR2CHTR2BCYP1A2HTR1A
	SCHEMBL3844310	0.84	HTR2B (0.39)	TYRABATENPP2HTR2CHTR2B
	SCHEMBL19658048	0.82	TYR (0.43)	TYRHTR2CHTR2BCYP1A2CA1
	SCHEMBL6401475	0.82	TYR (0.43)	TYRHTR2CHTR2BCYP1A2CYP2D6
	SCHEMBL11700185	0.80	GABRA1 (0.45)	TYRHTR2CHTR2BCYP1A2HTR1A
	SCHEMBL11402639	0.80	TYR (0.50)	TYRHTR2CHTR2BCYP1A2CA1
	SCHEMBL10587687	0.78	TYR (0.49)	TYRCYP3A4TSHR
	SCHEMBL3846424	0.78	SLC6A2 (0.45)	HTR2BCYP1A2LMNASLC6A2TAAR1
	SCHEMBL3842911	0.78	GAA (0.38)	CYP3A4TSHR
	SCHEMBL6415947	0.77	TYR (0.71)	TYRCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.