SCHEMBL3843395

SCHEMBL3843395

C#CCOc1c[c]ccc1OCC#C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
MAOB P27338 7/20 0.36
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2A6 P11509 1/20 0.35
HPGD P15428 2/20 0.34
TSHR P16473 1/20 0.34
LMNA P02545 1/20 0.34
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
GSTP1 P09211 1/20 0.33
CA1 P00915 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
MAOA P21397 2/20 0.32
KMT2A Q03164 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3088423 0.89 MAOB (0.40) MAPTMAOBPOLBCA12CA2
SCHEMBL16395165 0.85 MAOB (0.35) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL16395204 0.85 MAOB (0.35) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL16395549 0.83 MAPT (0.34) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL16395314 0.83 POLB (0.36) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL16395213 0.83 LMNA (0.44) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL16395215 0.83 LMNA (0.41) MAPTMAOBPOLBMAPK1HSD17B10
SCHEMBL15665401 0.78 CYP3A4 (0.33) MAPTMAOBCYP3A4CYP2A6
SCHEMBL15666437 0.77 NPC1 (0.39) MAPTPOLBMAPK1CYP3A4CYP2A6
SCHEMBL3547296 0.76 MAPT (0.33) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed