Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821889 | 0.86 | BRD4 (0.51) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL119901 | 0.86 | BRD4 (0.63) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL2811918 | 0.86 | BRD4 (0.63) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL15684270 | 0.86 | BRD4 (0.63) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL30307671 | 0.86 | BRD4 (0.63) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL3826960 | 0.83 | BRD4 (0.53) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| Glycerin SCHEMBL3843204 | 0.79 | POLB (0.83) | MAPTPOLBSMN1; SMN2KMT2AALDH1A1 | |
| Triethylene Glycol SCHEMBL1362131 | 0.78 | BRD4 (0.51) | MAPTBRD4POLBSMN1; SMN2KMT2A | |
| SCHEMBL29265031 | 0.77 | POLB (0.67) | MAPTPOLBSMN1; SMN2KMT2ACASP1 | |
| Glycerin SCHEMBL3844851 | 0.75 | POLB (0.45) | POLBSMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028247-A1 | Use of 1-alkyl-5-oxo-pyrrolidine-3-carbolic acid esters as gas hydrate inhibitors with improved biological degradability | CLARIANT INTERNATIONAL LTD. (CH) | 2009-02-25 | — | — | EP | disclosed |