Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL3843494 | 0.86 | MAPT (0.51) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL3829535 | 0.83 | POLB (0.67) | MAPTPOLBSMN1; SMN2KMT2AHTT | |
| SCHEMBL3822795 | 0.79 | BRD4 (0.61) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL3843491 | 0.77 | BRD4 (0.58) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL15684270 | 0.77 | BRD4 (0.63) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL119901 | 0.77 | BRD4 (0.63) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL30307671 | 0.77 | BRD4 (0.63) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL2811918 | 0.77 | BRD4 (0.63) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL3826960 | 0.74 | BRD4 (0.53) | BRD4MAPTPOLBSMN1; SMN2KMT2A | |
| SCHEMBL30282498 | 0.74 | BRD4 (0.67) | BRD4MAPTPOLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722589-B2 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT FINANCE (BVI) LIMITED (VG) | 2014-05-13 | — | — | US | disclosed |
| US-20090042747-A1 | Use of 1-alkyl-5-oxopyrrolidine-3-carboxylic esters as gas hydrate inhibitors with improved biodegradability | CLARIANT INTERNATIONAL LTD. | 2009-02-12 | — | — | US | disclosed |