Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981064 | 0.88 | GABRA1 (0.47) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL1420694 | 0.87 | GABRA1 (0.64) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL1244606 | 0.82 | GABRA1 (0.59) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL7737611 | 0.82 | GABRA1 (0.59) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL6309438 | 0.80 | GABRA1 (0.61) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL11766536 | 0.80 | GABRA1 (0.40) | GABRA1GABRB2POLBMEN1GAA | |
| SCHEMBL18191248 | 0.79 | GABRA1 (0.43) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL4633136 | 0.78 | GABRA1 (0.36) | GABRA1GABRB2POLBMEN1GAA | |
| SCHEMBL8522175 | 0.77 | POLB (0.44) | GABRA1GABRB2POLBSRD5A1MEN1 | |
| SCHEMBL1744767 | 0.77 | GABRA1 (0.58) | GABRA1GABRB2POLBSRD5A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1586598-B1 | Process for preparation of polymeric, phosphorus-containing compositions | INVISTA TECH SARL (CH) | 2009-09-09 | — | — | EP | disclosed |
| EP-1448503-B1 | PROCESS FOR PREPARING 3,3',6,6'-TETRAALKYL-2,2'-BIPHENOLS AND 3,3',6,6'-TETRAALKYL-5,5'-DIHALO-2,2'-BIPHENOLS | INVISTA TECH SARL (US) | 2008-01-30 | — | — | EP | disclosed |
| EP-1586598-A1 | Process for preparation of polymeric, phosphorus-containing compositions | E.I. du Pont de Nemours and Company (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1571172-A1 | Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | E.I. du Pont de Nemours and Company (US) | 2005-09-07 | — | — | EP | disclosed |
| CN-1617900-A | Polymeric phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | DU PONT (US) | 2005-05-18 | — | — | CN | disclosed |
| EP-1448668-A1 | POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E. I. du Pont de Nemours and Company (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20040049087-A1 | Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols | INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) | 2004-03-11 | — | — | US | disclosed |
| US-20030135014-A1 | Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA NORTH AMERICA S.A.R.L. | 2003-07-17 | — | — | US | disclosed |
| WO-2003046049-A1 | POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |
| US-6555718-B1 | Oxidatively coupling of phenols in presence of Lewis Acid catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-04-29 | — | — | US | disclosed |
| US-6489517-B1 | CHLORINATING DIALKYLPHENOL, OXIDATIVELY COUPLING PRODUCT IN POLAR APROTIC SOLVENT TO PRODUCE DICHLOROTETRAALKYLBIPHENOL, DECHLORINATING TO PRODUCE TETRAALKYLBIPHENOL, BROMINATING OR IODINATING IF DESIRED | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049087-A1 | Process for preparing 3,3',6,6'-tetraalkyl-2,2'-biphenols and 3,3',6,6'-tetraalkyl-5,5'-dihalo-2,2'-biphenols | CYP2B6, CYP26B1, UGT1A6 | GABRA1 841/4885GABRB2 607/4885POLB 653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.