SCHEMBL3843672

SCHEMBL3843672

C(=C/C12CC3CC(/C=C/c4ccccc4)(C1)CC(C14CC5CC(/C=C/c6ccccc6)(CC(/C=C/c6ccccc6)(C5)C1)C4)(C3)C2)\c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.34
KDM1A O60341 2/20 0.33
SIGMAR1 Q99720 2/20 0.31
GABBR2 O75899 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRB2 P47870 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
ALDH1A1 P00352 2/20 0.31
NFE2L2 Q16236 1/20 0.31
CYP19A1 P11511 1/20 0.31
MAOA P21397 1/20 0.31
TRPA1 O75762 1/20 0.31
LMNA P02545 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPK1 P28482 1/20 0.31
TSHR P16473 1/20 0.30
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844560 1.00 MAOB (0.34) MAOBKDM1ASIGMAR1GABBR2GABRB1
SCHEMBL3841511 0.97 MAOB (0.32) MAOBKDM1ASIGMAR1
SCHEMBL3841512 0.97 MAOB (0.32) MAOBKDM1ASIGMAR1
SCHEMBL3849792 0.94 GABBR2 (0.36) MAOBKDM1ASIGMAR1GABBR2GABRB1
SCHEMBL3849794 0.94 GABBR2 (0.36) MAOBKDM1ASIGMAR1GABBR2GABRB1
SCHEMBL3841872 0.92 GRIN2D (0.36) KDM1ASIGMAR1GABBR2GABRB1GABRB2
SCHEMBL3841870 0.92 GRIN2D (0.36) KDM1ASIGMAR1GABBR2GABRB1GABRB2
SCHEMBL3840995 0.85 GRIN2D (0.39) MAOBKDM1ASIGMAR1GABBR2GABRB1
SCHEMBL3841001 0.85 GRIN2D (0.39) MAOBKDM1ASIGMAR1GABBR2GABRB1
SCHEMBL3841598 0.84 GRIN2D (0.36) MAOBKDM1ASIGMAR1GABBR2GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090318610-A1 ORGANIC INSULATING MATERIALS, VARNISHES FOR ORGANIC INSULATING FILM EMPLOYING THEM, ORGANIC INSULATING FILMS AND SEMICONDUCTOR DEVICES SUMITOMO BAKELITE CO., LTD (JP) 2009-12-24 US disclosed
EP-2117009-A1 ORGANIC INSULATING MATERIAL, VARNISH FOR ORGANIC INSULATING FILM USING THE SAME, ORGANIC INSULATING FILM AND SEMICONDUCTOR DEVICE Sumitomo Bakelite Co., Ltd. (JP) 2009-11-11 EP disclosed