Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737001 | 0.86 | ROCK2 (0.35) | KMT2ARAB9AKDM4EROCK2MAPT | |
| Hydrochloric Acid SCHEMBL1736382 | 0.85 | ROCK2 (0.35) | KMT2ARAB9AKDM4EROCK2MAPT | |
| SCHEMBL1737240 | 0.83 | CDK4 (0.32) | KMT2ARAB9AROCK2MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL1736604 | 0.82 | CDK4 (0.32) | KMT2ARAB9AMAPTTDP1CYP1A2 | |
| SCHEMBL1736278 | 0.81 | KDM4E (0.32) | KMT2ARAB9AKDM4EROCK2MAPT | |
| Hydrochloric Acid SCHEMBL1736437 | 0.81 | KDM4E (0.32) | KMT2ARAB9AKDM4EROCK2CYP1A2 | |
| SCHEMBL1735560 | 0.77 | KMT2A (0.37) | KMT2ARAB9AKDM4EROCK2MAPT | |
| Hydrochloric Acid SCHEMBL1737735 | 0.76 | KMT2A (0.36) | KMT2ARAB9AKDM4EROCK2MAPT | |
| SCHEMBL1739802 | 0.74 | MAPT (0.42) | KMT2ARAB9AKDM4EMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL1735611 | 0.74 | MAPT (0.41) | KMT2ARAB9AKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |