Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50175 | 0.84 | — | — | |
| SCHEMBL2889072 | 0.84 | — | — | |
| SCHEMBL15651255 | 0.84 | TSHR (0.43) | TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL8067104 | 0.81 | — | — | |
| Propane SCHEMBL27421619 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL9543083 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL929894 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL28828349 | 0.78 | — | — | |
| Water SCHEMBL7740655 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL22437570 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208835-B1 | Non-sticky cosmetic moisturizer for skin and hair | UNILEVER PLC (GB) | 2009-10-28 | — | — | EP | disclosed |
| US-20080008730-A1 | COSMETIC COMPOSITIONS AND METHODS FOR REDUCING THE APPEARANCE OF PORES | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2008-01-10 | — | — | US | disclosed |
| EP-1699428-A1 | COSMETIC COMPOSITIONS AND METHODS FOR REDUCING THE APPEARANCE OF PORES | UNILEVER PLC (GB) | 2006-09-13 | — | — | EP | disclosed |
| US-6991799-B2 | Non-sticky cosmetic moisturizer for skin and hair | UNILEVER HOME & PERSONAL CARE USA DIVISION OF CONOPCO, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| WO-2005048958-A1 | COSMETIC COMPOSITIONS AND METHODS FOR REDUCING THE APPEARANCE OF PORES | UNILEVER PLC (GB) | 2005-06-02 | — | — | WO | disclosed |
| US-20050100568-A1 | Cosmetic compositions and methods for reducing the appearance of pores | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2005-05-12 | — | — | US | disclosed |
| US-20020131946-A1 | Non-sticky cosmetic moisturizer for skin and hair | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2002-09-19 | — | — | US | disclosed |
| EP-1208835-A2 | Non-sticky cosmetic moisturizer for skin and hair | UNILEVER PLC (GB) | 2002-05-29 | — | — | EP | disclosed |