Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762738 | 0.89 | ALDH1A1 (0.37) | MAPTGFERALDH1A1 | |
| SCHEMBL28318212 | 0.88 | ALDH1A1 (0.36) | MAPTGFERALDH1A1 | |
| SCHEMBL16431636 | 0.84 | ALDH1A1 (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3709439 | 0.71 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL27497138 | 0.68 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL9070282 | 0.67 | — | — | |
| SCHEMBL27661365 | 0.64 | TSHR (0.38) | MAPTGFERALDH1A1 | |
| SCHEMBL23340710 | 0.64 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2999035 | 0.64 | BRD4 (0.41) | MAPTGFERALDH1A1 | |
| SCHEMBL4583515 | 0.64 | BRD4 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940853-B1 | PROCESS FOR PREPARING 1 -HYDROXY-2 -SUBSTITUTED CYCLOHEXYL AZETIDIN-2-ONE COMPOUNDS | LEK PHARMACEUTICALS (SI) | 2009-11-04 | — | — | EP | claimed |