Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 12/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3839451 | 0.88 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| Hydrochloric Acid SCHEMBL3843858 | 0.88 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL3859505 | 0.77 | KCNH2 (0.54) | KCNH2TOP2A | |
| SCHEMBL3847249 | 0.72 | HRH4 (0.42) | KCNH2MPOPARP1PARP2 | |
| SCHEMBL3140710 | 0.68 | KCNH2 (0.63) | KCNH2TOP2ASLC2A1 | |
| SCHEMBL2931798 | 0.68 | KCNH2 (0.80) | KCNH2TOP2ASLC2A1 | |
| SCHEMBL2767080 | 0.67 | KCNH2 (0.70) | KCNH2TOP2A | |
| SCHEMBL5047682 | 0.67 | CCR3 (0.41) | CCR3 | |
| Hydrochloric Acid SCHEMBL2768395 | 0.67 | KCNH2 (0.69) | KCNH2TOP2A | |
| SCHEMBL5047895 | 0.67 | TSHR (0.43) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |