Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795246 | 0.92 | PTGER1 (0.71) | PTGER1 | |
| SCHEMBL3844835 | 0.90 | PTGER1 (0.61) | PTGER1 | |
| SCHEMBL4795243 | 0.82 | PTGER1 (0.70) | PTGER1 | |
| SCHEMBL3056778 | 0.81 | PTGER1 (0.84) | PTGER1 | |
| Hydrochloric Acid SCHEMBL3056914 | 0.81 | PTGER1 (0.84) | PTGER1 | |
| SCHEMBL3058098 | 0.79 | PTGER1 (0.65) | PTGER1 | |
| SCHEMBL3856745 | 0.77 | PTGER1 (0.49) | PTGER1 | |
| SCHEMBL13693327 | 0.77 | PTGER1 (0.98) | PTGER1 | |
| Hydrochloric Acid SCHEMBL4091864 | 0.76 | PTGER1 (1.00) | PTGER1 | |
| SCHEMBL13693326 | 0.76 | PTGER1 (0.89) | PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099782-A2 | ISOQUINOLINECARBOXAMIDES AS INHIBITORS OF STEAROYL-COA DESATURASE (SCD) | SmithKline Beecham Corporation (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008074834-A2 | ISOQUINOLINECARBOXAMIDES AS INHIBITORS OF STEAROYL-COA DESATURASE (SCD) | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |