Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3839763 | 1.00 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3838876 | 0.92 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL3842030 | 0.91 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL3844752 | 0.91 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3844569 | 0.91 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL3838504 | 0.91 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL3843415 | 0.91 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL3840898 | 0.90 | CRHR1 (0.53) | CRHR1 | |
| SCHEMBL3842548 | 0.89 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3843468 | 0.89 | CRHR1 (0.53) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446387-B1 | SUBSTITUTED ARYL 1,4-PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN CO LLC (US) | 2009-11-04 | — | — | EP | disclosed |