SCHEMBL384561

SCHEMBL384561

CC(C)(C)OOc1cccc(C(=O)OO)c1OOC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ELANE P08246 2/20 0.36
MAPK1 P28482 1/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KDM4E B2RXH2 3/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
SLC6A3 Q01959 1/20 0.31
ESR1 P03372 2/20 0.31
ITGB3 P05106 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28987721 0.86 HSD17B10 (0.38) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL346597 0.85 MAPK1 (0.50) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL2507510 0.85 HSD17B10 (0.44) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL17273601 0.84 TSHR (0.38) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL28518702 0.75 HSD17B10 (0.49) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL29288745 0.74 HSD17B10 (0.53) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL28567814 0.74 TSHR (0.41) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL2000365 0.74 ALDH1A1 (0.47) HSD17B10ALDH1A1TSHRTDP1MAPK1
SCHEMBL31571285 0.74 ELANE (0.58) HSD17B10ALDH1A1TSHRTDP1ELANE
SCHEMBL153852 0.73 KDM4E (0.55) HSD17B10ALDH1A1TSHRTDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3476563-B1 JOINED BODY AND METHOD FOR MANUFACTURING SAME ENEOS MAT CORPORATION (JP) 2023-08-02 EP disclosed
US-20200307115-A1 JOINED BODY AND METHOD FOR MANUFACTURING SAME JSR CORPORATION (JP) 2020-10-01 US disclosed
EP-3476563-A1 JOINED BODY AND METHOD FOR MANUFACTURING SAME JSR Corporation (JP) 2019-05-01 EP disclosed
US-10144820-B2 Crosslinked rubber, member for tires, vibration-proofing member, member for belts, and rubber composition JSR CORPORATION (JP) 2018-12-04 US disclosed
EP-3064545-B1 MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER AND MEMBER FOR BELTS JSR CORP (JP) 2018-06-20 EP disclosed
US-20170233561-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2017-08-17 US disclosed
US-9683095-B2 Crosslinked rubber, member for tires, vibration-proofing member, member for belts, and rubber composition JSR CORPORATION (JP) 2017-06-20 US disclosed
EP-3064545-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR Corporation (JP) 2016-09-07 EP disclosed
US-20160215127-A1 CROSSLINKED RUBBER, MEMBER FOR TIRES, VIBRATION-PROOFING MEMBER, MEMBER FOR BELTS, AND RUBBER COMPOSITION JSR CORPORATION (JP) 2016-07-28 US disclosed
EP-1958980-B1 THERMOPLASTIC ELASTOMER COMPOSITION, FOAM PRODUCT, AND PROCESS FOR PRODUCTION OF THE COMPOSITION OR FOAM PRODUCT JSR CORP (JP) 2012-10-31 EP disclosed
US-20020183441-A1 Thermoplastic elastomer composition JSR CORPORATION (JP) 2002-12-05 US disclosed
EP-1195404-A1 THERMOPLASTIC ELASTOMER COMPOSITION JSR Corporation (JP) 2002-04-10 EP disclosed
US-6077878-A FOAMED EXTRUDATE COMPRISING GRAFTED COPOLYMER OF POLYPROPYLENE RESIN AND AROMATIC VINYL MONOMER KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-06-20 US disclosed
EP-0735091-B1 Thermoplastic elastomer composition excellent in fusion bondability with an olefinic rubber, and bonded article JAPAN SYNTHETIC RUBBER CO LTD (JP) 1999-12-22 EP disclosed
EP-0735091-A2 Thermoplastic elastomer composition excellent in fusion bondability with an olefinic rubber, and bonded article JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-10-02 EP disclosed
US-5128413-A Ethylene-ethylidenenorbornene-propylene terpolymer blend; injection fusion bondability; surface gloss MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed
EP-0132931-B1 THERMOPLASTIC ELASTOMER COMPOSITION AND PROCESS FOR PREPARATION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-22 EP disclosed
US-4906694-A Thermoplastic elastomer composition and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-06 US disclosed
US-4650830-A INJECTION FUSION BONDABILITY, GLOSS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-03-17 US disclosed
EP-0132931-A2 Thermoplastic elastomer composition and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-02-13 EP disclosed