SCHEMBL384570

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10107034	0.82	HRH3 (0.42)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL382949	0.80	KDM4E (0.51)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL383483	0.80	KDM4E (0.51)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL385239	0.80	KDM4E (0.48)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL384302	0.80	SERPINE1 (0.58)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL16433607	0.80	HRH3 (0.46)	GPR119HRH3KDM4EABL1LMNA
	SCHEMBL2550775	0.79	GPR119 (0.65)	GPR119GAAHRH3KDM4EABL1
	SCHEMBL12283002	0.79	GPR119 (0.65)	GPR119GAAHRH3KDM4EABL1
	SCHEMBL19892721	0.78	KDM4E (0.57)	GPR119GAAHRH3KDM4EABL1
	SCHEMBL16433597	0.76	SERPINE1 (0.53)	GPR119HRH3KDM4EABL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.