Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.45 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3869431 | 0.98 | PPARA (0.41) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3848566 | 0.96 | PPARA (0.39) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3845359 | 0.94 | PPARA (0.50) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3847187 | 0.92 | PPARA (0.44) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3840790 | 0.92 | PPARA (0.46) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841400 | 0.91 | PPARA (0.49) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841911 | 0.91 | PPARA (0.52) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3848673 | 0.90 | PPARA (0.44) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3842663 | 0.89 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL3845631 | 0.88 | PPARA (0.44) | PPARAPPARGPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |